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1

Application of Imaging Flow Cytometry for the Characterization of Intracellular Attributes in Chinese Hamster Ovary Cell Lines at the Single Cell Level

Pekle, Eva, Smith, Andrew, Rosignoli, Guglielmo, Sellick, Christopher, Smales, C. Mark, Pearce, Claire

Journal:

Biotechnology Journal

Year:

2019

Language:

english

File:

PDF, 395 KB

english, 2019

2

The cold-shock response in cultured mammalian cells: Harnessing the response for the improvement of recombinant protein production

Mohamed B Al-Fageeh, Rosalyn J Marchant, Martin J Carden, C Mark Smales

Journal:

Biotechnology and Bioengineering

Year:

2006

Language:

english

File:

PDF, 124 KB

english, 2006

3

Therapeutic Proteins Volume 308 || Isolation, Solubilization, Refolding, and Chromatographic Purification of Human Growth Hormone from Inclusion Bodies of Escherichia coli Cells: A Case Study

Smales, C. Mark, James, David C.

Year:

2005

Language:

english

File:

PDF, 168 KB

english, 2005

4

Measurement and control of host cell proteins (HCPs) in CHO cell bioprocesses

Hogwood, Catherine EM, Bracewell, Daniel G, Smales, C Mark

Journal:

Current Opinion in Biotechnology

Year:

2014

Language:

english

File:

PDF, 431 KB

english, 2014

5

Wind and Wildlife || Predicting the Weather-Dependent Collision Risk for Birds at Wind Farms

Hull, Cindy, Bennett, Emma, Stark, Elizabeth, Smales, Ian, Lau, Jenny, Venosta, Mark

Year:

2015

Language:

english

File:

PDF, 967 KB

english, 2015

6

Therapeutic Proteins Volume 308 || Characterization of Interferon a2B Pegylated via Carboxyalkylation: A Case Study

Smales, C. Mark, James, David C.

Year:

2005

Language:

english

File:

PDF, 168 KB

english, 2005

7

Therapeutic Proteins Volume 308 || Probing Reversible Self-Association of Therapeutic Proteins by Sedimentation Velocity in the Analytical Ultracentrifuge

Smales, C. Mark, James, David C.

Year:

2005

Language:

english

File:

PDF, 199 KB

english, 2005

8

Therapeutic Proteins Volume 308 || Virus Elimination and Validation

Smales, C. Mark, James, David C.

Year:

2005

Language:

english

File:

PDF, 98 KB

english, 2005

9

The future of host cell protein (HCP) identification during process development and manufacturing linked to a risk-based management for their control

Bracewell, Daniel G., Francis, Richard, Smales, C. Mark

Journal:

Biotechnology and Bioengineering

Year:

2015

Language:

english

File:

PDF, 693 KB

english, 2015

10

Urban Design Strategies in Practice || Tapping into Local Talent: The Production of the Leeds City Centre Urban Design Strategy

LINDSAY SMALES and MARK BURGESS

Journal:

Built Environment

Year:

1999

Language:

english

File:

PDF, 6.11 MB

english, 1999

11

Methionine Sulfoximine Supplementation Enhances Productivity in GS-CHOK1SV Cell Lines through Glutathione Biosynthesis

Feary, Marc, Racher, Andrew J, Young, Robert J, Smales, C Mark

Journal:

Biotechnology Progress

Year:

2016

Language:

english

File:

PDF, 1.45 MB

english, 2016

12

A classification of the geothermal vegetation of the Taupō Volcanic Zone, New Zealand

Smale, Mark C., Wiser, Susan K., Bergin, Michael J., Fitzgerald, Neil B.

Journal:

Journal of the Royal Society of New Zealand

Year:

2017

Language:

english

File:

PDF, 2.39 MB

english, 2017

13

Repeated Melatonin Supplementation Improves Sleep in Hypertensive Patients Treated with Beta-Blockers: A Randomized Controlled Trial

Scheer, Frank A.J.L., Morris, Christopher J., Garcia, Joanna I., Smales, Carolina, Kelly, Erin E., Marks, Jenny, Malhotra, Atul, Shea, Steven A.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.10 MB

english, 2012

14

Demand for Genetic Resources and the U.S. National Plant Germplasm System

Rubenstein, Kelly Day, Smale, Melinda, Widrlechner, Mark P.

Journal:

Year:

2006

File:

PDF, 360 KB

2006

15

Protein modification during antiviral heat bioprocessing

C. Mark Smales, Duncan S. Pepper, David C. James

Journal:

Biotechnology and Bioengineering

Year:

2000

Language:

english

File:

PDF, 223 KB

english, 2000

16

Protein modification during anti-viral heat-treatment bioprocessing of factor VIII concentrates, factor IX concentrates, and model proteins in the presence of sucrose

C. Mark Smales, Duncan S. Pepper, David C. James

Journal:

Biotechnology and Bioengineering

Year:

2002

Language:

english

File:

PDF, 305 KB

english, 2002

17

eIF2α phosphorylation, stress perception, and the shutdown of global protein synthesis in cultured CHO cells

Michèle F. Underhill, John R. Birch, C. Mark Smales, Louise H. Naylor

Journal:

Biotechnology and Bioengineering

Year:

2005

Language:

english

File:

PDF, 648 KB

english, 2005

18

Functional proteomic analysis of GS-NS0 murine myeloma cell lines with varying recombinant monoclonal antibody production rate

Diane M. Dinnis, Scott H. Stansfield, Stefan Schlatter, C. Mark Smales, Daniel Alete, John R. Birch, Andrew J. Racher, Carol T. Marshall, Lars K. Nielsen, David C. James

Journal:

Biotechnology and Bioengineering

Year:

2006

Language:

english

File:

PDF, 406 KB

english, 2006

19

Identification of the limitations on recombinant gene expression in CHO cell lines with varying luciferase production rates

Emma J. Mead, Lesley M. Chiverton, C. Mark Smales, Tobias von der Haar

Journal:

Biotechnology and Bioengineering

Year:

2009

Language:

english

File:

PDF, 234 KB

english, 2009

20

Post-translational events of a model reporter protein proceed with higher fidelity and accuracy upon mild hypothermic culturing of Chinese hamster ovary cells

Rosalyn J. Masterton, Anne Roobol, Mohamed B. Al-Fageeh, Martin J. Carden, C. Mark Smales

Journal:

Biotechnology and Bioengineering

Year:

2010

Language:

english

File:

PDF, 347 KB

english, 2010

21

Transient expression of human TorsinA enhances secretion of two functionally distinct proteins in cultured Chinese hamster ovary (CHO) cells

Lyne Jossé, C. Mark Smales, Mick F. Tuite

Journal:

Biotechnology and Bioengineering

Year:

2010

Language:

english

File:

PDF, 491 KB

english, 2010

22

Erratum: Post-translational events of a model reporter protein proceed with higher fidelity and accuracy upon mild hypothermic culturing of Chinese hamster ovary cells

Rosalyn J. Masterton, Anne Roobol, Mohamed B. Al-Fageeh, Martin J. Carden, C. Mark Smales

Journal:

Biotechnology and Bioengineering

Year:

2011

File:

PDF, 38 KB

2011

23

Investigating variables and mechanisms that influence protein integrity in low water content amorphous carbohydrate matrices

Jane F. Povey, Natalia Perez-Moral, Timothy R. Noel, Roger Parker, Mark J. Howard, C. Mark Smales

Journal:

Biotechnology Progress

Year:

2009

Language:

english

File:

PDF, 316 KB

english, 2009

24

Use of ion-exchange and hydrophobic-interaction chromatography for the rapid purification of lysozyme—estrone glucuronide conjugates

C. Mark Smales, Delwyn Cooke, Leonard F. Blackwell

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1994

Language:

english

File:

PDF, 1.07 MB

english, 1994

25

On the statistical analysis of the GS-NS0 cell proteome: Imputation, clustering and variability testing

Norhaiza Ahmad, Jian Zhang, Phillip J. Brown, David C. James, John R. Birch, Andrew J. Racher, C. Mark Smales

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2006

Language:

english

File:

PDF, 270 KB

english, 2006

26

Ecological Restoration of Native Forest at Aratiatia, North Island, New Zealand

Mark C. Smale, Patrick T. Whaley, Paul N. Smale

Journal:

Restoration Ecology

Year:

2001

Language:

english

File:

PDF, 2.41 MB

english, 2001

27

Global changes in gene expression observed at the transition from growth to stationary phase in Listeria monocytogenes ScottA batch culture

Mark E. Weeks, David C. James, Gary K. Robinson, C. Mark Smales

Journal:

Year:

2004

Language:

english

File:

PDF, 318 KB

english, 2004

28

Proteomic analysis of enriched microsomal fractions from GS-NS0 murine myeloma cells with varying secreted recombinant monoclonal antibody productivities

Daniel E. Alete, Andrew J. Racher, John R. Birch, Scott H. Stansfield, David C. James, C. Mark Smales

Journal:

Year:

2005

Language:

english

File:

PDF, 1.51 MB

english, 2005

29

Evaluation of protein modification during anti-viral heat bioprocessing by electrospray ionization mass spectrometry

C. Mark Smales, Duncan S. Pepper, David C. James

Journal:

Rapid Communications in Mass Spectrometry

Year:

2001

Language:

english

File:

PDF, 163 KB

english, 2001

30

The cold-shock response in mammalian cells: investigating the HeLa cell cold-shock proteome

Michèle F. Underhill, C. Mark Smales

Journal:

Year:

2007

Language:

english

File:

PDF, 187 KB

english, 2007

31

Metabolic Rates, Growth Phase, and mRNA Levels Influence Cell-Specific Antibody Production Levels from In Vitro-Cultured Mammalian Cells at Sub-Physiological Temperatures

Rosalyn J. Marchant, Mohamed B. Al-Fageeh, Michele F. Underhill, Andrew J. Racher, C. Mark Smales

Journal:

Molecular Biotechnology

Year:

2008

Language:

english

File:

PDF, 325 KB

english, 2008

32

Proceedings from the 8th PEACe Conference on Protein Expression in Animal Cells, Angra Dos Reis, Brazil, September 16–20, 2007

Journal:

Molecular Biotechnology

Year:

2008

Language:

english

File:

PDF, 70 KB

english, 2008

33

Erratum to: Metabolic Rates, Growth Phase, and mRNA Levels Influence Cell-Specific Antibody Production Levels from In Vitro-Cultured Mammalian Cells at Sub-Physiological Temperatures

Rosalyn J. Marchant, Mohamed B. Al-Fageeh, Michele F. Underhill, Andrew J. Racher, C. Mark Smales

Journal:

Molecular Biotechnology

Year:

2011

Language:

english

File:

PDF, 1.50 MB

english, 2011

34

Seed bed treatment effects on vegetation and seedling establishment in a New Zealand pasture one year after seeding with native woody species

Bryan A. Stevenson, Mark C. Smale

Journal:

Ecological Management & Restoration

Year:

2005

Language:

english

File:

PDF, 326 KB

english, 2005

35

Climate, landscape and microenvironment interact to determine plant composition in naturally discrete gravel beach communities

Susan K. Wiser, Rowan P. Buxton, Beverley R. Clarkson, Sarah J. Richardson, G. M. Rogers, Mark C. Smale, Peter A. Williams

Journal:

Journal of Vegetation Science

Year:

2010

Language:

english

File:

PDF, 375 KB

english, 2010

36

Biochemical insights into the mechanisms central to the response of mammalian cells to cold stress and subsequent rewarming

Anne Roobol, Martin J. Carden, Ray J. Newsam, C. Mark Smales

Journal:

Year:

2009

Language:

english

File:

PDF, 990 KB

english, 2009

37

Protein Modifications during Antiviral Heat Bioprocessing and Subsequent Storage

C. Mark Smales, Duncan S. Pepper, David C. James

Journal:

Biotechnology Progress

Year:

2001

Language:

english

File:

PDF, 79 KB

english, 2001

38

Transient Gene Expression Levels from Multigene Expression Vectors

Michèle F. Underhill, C. Mark Smales, Louise H. Naylor, John R. Birch, David C. James

Journal:

Biotechnology Progress

Year:

2007

Language:

english

File:

PDF, 348 KB

english, 2007

39

Noncovalently linked nuclear localization peptides for enhanced calcium phosphate transfection

Evdoxia Gourbatsi, Mohamed B. Al-Fageeh, Rosalyn J. Marchant, Sarah J. Scott, Michèle F. Underhill, C. Mark Smales

Journal:

Molecular Biotechnology

Year:

2006

Language:

english

File:

PDF, 225 KB

english, 2006

40

Proceedings from the 7th PEACe Conference on Protein Expression in Animal Cells, September 18–22, 2005, Crete, Greece

Mark Smales, Kenneth Lundstrom

Journal:

Molecular Biotechnology

Year:

2006

Language:

english

File:

PDF, 82 KB

english, 2006

41

On the effect of transient expression of mutated elF2α and elF4E eukaryotic translation initiation factors on reporter gene expression in mammalian cells upon cold-shock

Michèle F. Underhill, Rosalyn J. Marchant, Martin J. Carden, David C. James, C. Mark Smales

Journal:

Molecular Biotechnology

Year:

2006

Language:

english

File:

PDF, 184 KB

english, 2006

42

Mechanisms of protein modification during model anti-viral heat-treatment bioprocessing of β-lactoglobulin variant A in the presence of sucrose

C. Mark Smales, Duncan S. Pepper, David C. James

Journal:

Biotechnology and Applied Biochemistry

Year:

2000

Language:

english

File:

PDF, 180 KB

english, 2000

43

Purification and characterization of lysozyme-pregnanediol glucuronide conjugates: the effect of the hapten and coupling reagent on the substitution level, sites of acylation and the consequences for the development of future immunoassays

C. Mark Smales, Leonard F. Blackwell

Journal:

Biotechnology and Applied Biochemistry

Year:

2002

Language:

english

File:

PDF, 161 KB

english, 2002

44

Therapeutic Proteins Volume 308 || Large-Scale Transient Expression of Therapeutic Proteins in Mammalian Cells

Smales, C. Mark, James, David C.

Year:

2005

Language:

english

File:

PDF, 116 KB

english, 2005

45

Therapeutic Proteins Volume 308 || Site-Specific Integration for High-Level Protein Production in Mammalian Cells

Smales, C. Mark, James, David C.

Year:

2005

Language:

english

File:

PDF, 121 KB

english, 2005

46

Therapeutic Proteins Volume 308 || Production of Recombinant Therapeutic Proteins by Mammalian Cells in Suspension Culture

Smales, C. Mark, James, David C.

Year:

2005

Language:

english

File:

PDF, 109 KB

english, 2005

47

Therapeutic Proteins Volume 308 || Extraction and Denaturing Gel Electrophoretic Methodology for the Analysis of Yeast Proteins

Smales, C. Mark, James, David C.

Year:

2005

Language:

english

File:

PDF, 244 KB

english, 2005

48

Host cell protein adsorption characteristics during protein a chromatography

Richard D. R. Tarrant, M. Lourdes Velez-Suberbie, Andrew S. Tait, C. Mark Smales, Daniel G. Bracewell

Journal:

Biotechnology Progress

Year:

2012

Language:

english

File:

PDF, 935 KB

english, 2012

49

Ethane hydrogenolysis over well-defined RuCuSiO2 catalysts

Mark W. Smale, Terry S. King

Journal:

Journal of Catalysis

Year:

1989

Language:

english

File:

PDF, 845 KB

english, 1989

50

Kinetics of ethane hydrogenolysis over silica-supported ruthenium-group IB metal catalysts

Mark W. Smale, Terry S. King

Journal:

Journal of Catalysis

Year:

1990

Language:

english

File:

PDF, 2.37 MB

english, 1990

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